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★★★★★
4.8/5 (17,700+ reviews)
0
#1 Rated Nerve Relief Cream* ★★★★★★★★★★ 4.8/5 · 17,700+ reviews

Calm the burning and tingling that's keeping you up at night.

Fast-absorbing magnesium cream for burning, tingling feet - non‑greasy and easy to apply before bed.

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Neuropura Total Relief

Is the burning and tingling in your feet
a sign of something deeper?

If you’re waking up with burning, tingling, or numbness in your feet and legs, it’s often more than just a “part of getting older.” Millions of adults over 55 live with nerve discomfort that disrupts their sleep and slows them down day after day.

Ignoring it can make the days longer and the nights harder. Prescription routes can be expensive and come with side effects, while most creams at the drugstore feel greasy and wear off fast. Finding a gentle, daily option you can trust is what makes the difference.

Real Customers, Real Relief

Join over 52,000 people worldwide who've made Neuropura Total Relief part of their nightly routine

Liam W. - verified Neuropura customer

"My feet were burning so bad I couldn't wear socks. Now I can garden again and the tingling has calmed down a lot. Wish I'd found this sooner."

Ruby T. - verified Neuropura customer

"I've been using this for 3 weeks and I'm finally sleeping through the night. The burning in my feet had been keeping me up constantly. This actually works when nothing else did."

Harper C. - verified Neuropura customer

"Skeptical at first after trying everything. Applied it before bed and actually slept through for the first time in months. Already ordered 3 more jars."

Sharon P. - verified Neuropura customer

"I can finally take walks with my grandchildren again. The pins and needles have calmed down a lot. This cream changed everything for our family."

Gary M. - verified Neuropura customer

"After cancer treatment my hands and feet never felt right. I'd tried everything without much luck. This has made a real difference and I'm grateful for it."

Amelia H. - verified Neuropura customer

"Other options I tried left me feeling foggy and unwell. This cream is gentle, easy to apply, and I feel more like myself. My wife notices a difference too."

How Neuropura compares

Designed for people who haven't found what works

We know you've tried things that promised a lot and left you disappointed. We created this formula for people looking for a gentler option to add to their routine.

Neuropura Total Relief

Neuropura Total Relief

  • Works locally where you apply it
  • Absorbs in minutes
  • Magnesium chloride + botanicals
  • Safe for long-term daily use
  • Apply exactly where you need it
  • No drowsiness, no fog
  • Non-greasy, no residue on sheets
  • Natural ingredients, no harsh chemicals
Pills, prescription bottles, and ordinary creams that didn't work

Pills & Other Creams

  • Takes weeks to notice changes
  • Results vary widely
  • Often masks rather than soothes
  • May cause drowsiness or fog
  • Systemic side effects common
  • Temporary numbing only
  • Full-body effects
  • Often contain harsh additives
Neuropura Total Relief jar
About us

Years of searching for a product worth putting our name on. That's what it took.

We talked to manufacturers who wanted us to invest in heavy glass, embossed lids, gold foil boxes - ten times more on packaging than we'd planned. We said no. We don't care how the jar looks. We care what's inside it.

So we went simple. A clean label, a plain jar, and everything that would've gone into the packaging went into the formula instead.

Five ingredients. Magnesium chloride, frankincense, arnica, MSM, aloe, with shea butter to carry them. Nothing extra. Nothing you can't pronounce.

A 2023 pilot study in the Journal of Palliative Medicine tested transdermal magnesium chloride (the primary active in our formula) on patients with peripheral neuropathy. After 12 weeks, symptom scores dropped significantly, and blood magnesium levels stayed flat, suggesting it was working locally in the tissue rather than systemically. Early research on a small group, but it's the direction the evidence is pointing.

If you've been let down by every cream you've tried, we think this one will surprise you. That's why we made it.

★★★★★ 4.8/5 · 17,757 reviews

Neuropura - Total Relief Soothing Nerve Cream

Soothing cream with magnesium chloride, arnica, frankincense, MSM, and aloe vera in a shea butter base - calming botanicals for targeted daily comfort. Non-greasy and easy to apply. 50g per jar.

  • Comfort that lasts through the day and night
  • Soothes burning, tingling, and discomfort
  • Supports a deep, restful night's sleep
  • Natural ingredients, gentle on skin
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Raw, unedited Facebook comments

Real customers, real results

Neuropura Total Relief - Community Reviews
Total Relief Soothing Nerve Cream
Karen Thompson
After 8 months of rough sleep, my legs at night were unbearable. It felt like ants crawling under my skin mixed with this deep ache I couldn't shake. The tossing and turning kept me awake most nights and I was getting desperate. I was told it might just be age and to live with it. Found Neuropura's Total Relief cream and decided to try it. Within the first week, I noticed I was falling asleep faster. Now after 2 months of nightly use, I'm sleeping 7-8 hours straight and actually wake up rested. The leg twitching has calmed down a lot. I tell everyone in my group about this cream now.
LikeReply3w
Patricia Williams
5 stars!!! My legs were getting so restless I couldn't sit through a movie. Now thanks to Neuropura's Total Relief cream, my husband and I are back to our nightly walks and I actually sleep 🙏
LikeReply2w
Kathy Martinez
This cream is a lifesaver. My nights were so bad I couldn't fall asleep without my mind racing for hours. Now I'm sleeping 6-7 hours straight. Worth every penny!
LikeReply2w
Dorothy Wilson
I'm 68 and have been dealing with bad sleep for years. This cream is the first thing I've tried that hasn't left me feeling groggy the next morning. I can finally play with my grandkids at the park instead of napping through their visits.
LikeReply1w
Michael Torres
Skeptical at first but it really works. Been 4 nights now and the tension in my calves has gone from unbearable to barely there. Finally something that actually helps me settle into sleep.
LikeReply1w
Rose Mitchell
This cream absorbs really fast and doesn't leave any residue like other lotions I've tried, and it actually works. I was dealing with constant night-time muscle cramps and tension that was making my life miserable. After using this for a few weeks, I'm getting real sleep for the first time in months. Finally something that delivers on its promises!
LikeReply6d
Carol Jensen
This product is the best! The restless legs feeling has settled down so much!
LikeReply5d
Nancy Peterson
I wanted to avoid adding more medications to my routine. My legs at night were like ants crawling under my skin. Now I apply this before bed every night. It's not a miracle but the difference is real. I feel like myself again!
LikeReply4d
Thomas Greene
Stress gave me bad sleep 2 years ago. I'd started to think I'd have to live with it. Glad I was wrong. This cream has made a real difference. Can sleep through the night and actually cook Sunday dinner for the family again.
LikeReply3d
Isabella Rossi
Been using this for 2 weeks now. The leg twitching has calmed way down and I'm sleeping through the night again. Thank you Neuropura!
LikeReply2w
Thomas Brennan
Had bad sleep for 8 years. Tried melatonin, magnesium pills, and every supplement on Amazon. This cream is different. It actually absorbs and works where the tension is. My legs feel calm again, not like I've had ten cups of coffee.
LikeReply2w
William Jackson
I've been dealing with low energy and poor sleep for 12 years. The racing thoughts at night and muscle tension in my shoulders were making it hard to function normally. Had tried several things over the years with mixed results. Started using Neuropura's Total Relief cream on the advice of someone in my support group. Been applying it to my shoulders and legs nightly for about 10 weeks now. The tension has eased up quite a bit and falling asleep is so much easier. Really happy with the results.
LikeReply1w
Paul Mitchell
Other options I'd tried made me feel foggy 24/7 and barely touched the problem. Switched to this cream and got actual rest without feeling like a zombie. The restlessness and tension are so much better and I can think clearly again. Glad I found something gentler.
LikeReply1w
Jennifer Walsh
My mom had a rough stretch health-wise and her sleep never recovered. She went from independent to exhausted all day. Tried everything for rest, but nothing worked. Got her Neuropura's Total Relief cream and within 15 minutes she said “the tension is easing.” After 2 weeks she said the leg cramps had calmed down a lot. This gave me my mom back.
LikeReply6d
Karen Stevens
I've had trouble with restless legs for 3 years now. The urge to move them constantly was unbearable. My husband was ready to sleep in another bed. This cream helps settle things down within 20 minutes. I sleep through the night again and we're back in the same bed together.
LikeReply4d
Patricia Hendricks
This cream WORKS!!!! Just ordered my third jar. My legs feel so much calmer at night. Wish I'd found Neuropura Total Relief years ago.
LikeReply2d
Neuropura Promise

If it doesn't work for you, we'll offer a full refund within 90 days.

Common Questions

Everything you need to know

How fast will I feel relief?
Many customers notice a calming effect within the first 15-30 minutes of application. In the first days, you may feel a soothing sensation shortly after each use. By week 2-3, many report the feeling becomes more consistent and longer-lasting. Results vary from person to person.
Is this safe for diabetics?
Neuropura is a topical cream with natural ingredients and is not absorbed into the bloodstream in meaningful amounts. Many of our customers have diabetes. As always, if you have specific medical concerns or are taking prescription medication, please check with your doctor first.
What makes this different from other magnesium creams?
Many magnesium creams use lower-concentration magnesium sulfate. We use high-quality magnesium chloride combined with frankincense, arnica, MSM, and aloe vera in a shea butter base - a five-ingredient blend designed for smooth absorption and a calming feel.
What if it doesn't work for me?
You're covered by our 90-day money-back guarantee. If you don't notice a difference, just email us and we'll refund every cent - no questions asked, no complicated return process.
Are there any side effects?
Neuropura Total Relief is made with natural, skin-safe ingredients. Because it's topical, it isn't associated with the systemic side effects common to oral options. Some people notice a mild tingling on application, which is normal as the magnesium absorbs. Discontinue use if irritation occurs.
Is there research behind topical magnesium?
Yes, early clinical research exists. A 2023 pilot study published in the Journal of Palliative Medicine tested transdermal magnesium chloride (the primary active in Neuropura) on patients with peripheral neuropathy. Participants applied it daily for 12 weeks. Symptom scores dropped significantly by week 8, and blood magnesium levels didn't change, suggesting the magnesium was working locally in the tissue rather than entering the bloodstream. It's a small pilot study, not a definitive trial, but it points in the direction our customers already report.

Athavale A, Miles N, Pais R, Snelling P, Chadban SJ. "Transdermal Magnesium for the Treatment of Peripheral Neuropathy in Chronic Kidney Disease." J Palliat Med. 2023;26(12):1654-1661. PMID: 37486715.
Shipping & delivery

📦 Shipping rates
FREE shipping on all orders worldwide.
No additional import duties or tariffs will be imposed.

⏱️ Delivery times
Worldwide delivery: 7-14 days.
Tracking: email confirmation sent when your order ships.

ℹ️ Processing note
Due to the popularity of our premium formula, we hand-select each batch for quality. This may add 1-2 business days to processing, ensuring you receive the freshest, most effective product.

Neuropura Total Relief

Calm the burning. Reclaim your nights.

Join 52,000+ people worldwide who've made Neuropura Total Relief part of their nightly routine.

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